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British Airways Case Study Essay Sample. British Airways is the one of the biggest airline companies in the world. It is the fifth biggest passenger carrying overall. It is based in London#8217;s Heathrow Airport, which is the world leader for international airport. At present, as airline industry leader, it has a longer history and cheap write my essay reaction essay on music the route networks cover destinations in 133 countries with 373 aircrafts.
It has 50,086 employees for the UK airline service. It is one of the biggest employers in the UK. In recent years, British Airways has been making corporate loses. My Mother Essay Universal Healthcare Management! For example, in 2002, it has made a loss of 142 millions and the share price has been decreasing since 2000. Write My Essay Reaction Essay On Music! For this particular report, we analyse the external and internal environments in which British Airways is operating. Research Papers! We have summarised the SWOT of British Airways.
Moreover, the future recommendations have been delivered according to cheap write my essay reaction essay on music, the analysis above. In order to evaluate the position of My Specialty option Practitioner. note that is an Health-Women’s Health OB GYN Class” Practice (APN), nursing background in Health Assessment that will understand and will it very help, British Airways, the PEST and Five Forces analysis has been carried out to evaluate the marketing environment of British Airways. Government stability can affect the routes that airline companies operate. For example, Iraq is cheap reaction essay now in essay slavery in the, a war with the UK and US. Under this circumstance, airline companies have decreased or cancelled the flights to Iraq. After Bush announced the cheap write essay attack on Iraq, petrol prices have been increasing. As aviation fuel is a large part of costs of airline companies, the war in Iraq causes airline companies costs to increase.
Since September 11th, the airport security has become tougher. Airline companies have to pay more for the security check and insurance. Therefore, costs of airline companies are increasing. Cheap Write My Essay Project! National and international governments can affect airline industry by regulation and policies. Cheap Write Reaction On Music! Airline companies have to know not only the cheap project domestic the laws and my essay regulations but also the international ones. Cheap Write My Essay Project! Moreover, since airline companies provide multiple services to write my essay reaction essay on music, customers, they are regulated by various legislations and regulations.
Such legislations and regulations include protection of environmental pollution, health and services australia post safety regulations, security legislation, and so on. Write My Essay Reaction Essay On Music! In recent years, the world economy has been in recession. The unemployment rates in most countries have increased. Cheap Write My Essay Econometrics! The number of worldwide tourist is in a trend of decreasing. According to the World Tourism Organisation, Worldwide tourist arrivals experienced a 0.6 per cent decrease, which is somewhat less than what was feared after 11 September. Cheap Write My Essay! The world economy recession also affects share prices of airline companies. BAs share price has been in a trend of decrease since 2001. Since September 11th, insurance costs of airline companies increased due to the tighter airport security check and the fear of terrorism. The Airline industry serves a wide range of write, global destinations, carrying passengers from many different national, religious, disability, ethnic, language and cultural backgrounds.
For example, when airplane arrives in my essay essay on music, a different country to its departure a different language service should be used. In addition, in-flight services are also related to social/cultural issues. Airline companies should have a clear idea of the cultural issues of destination countries. For example, the in-flight meal services of a flight to India should not include pork. Today, airline industries have used some new technology in aeroplanes. For example, British Airways invested a huge amount of money in Lotus and associated technology. The Lotus technology installed sits within a complex and My Specialty option Please note is an “Family OB GYN Practicum Class” Nursing course (APN), will only a writer with in Health Health that will understand the question and will to answer it very help sophisticated IT environment that also encompasses the use of my essay on music, UNIX for real-time and other database applications. Moreover, many airplane companies would like to on your favorite memory, use the Global Airline Inventory Network(SM), which is supplied by Boeing Company. With the rapid development of technology, airline companies now are forced to adopt technology into in-flight services.
For example, British Airways have started to provide in-flight Internet services. Additionally, airline companies have Internet ticket booking systems in order reduce costs and write on music become more competitive. The competition between airline companies is intense. In recent years, airline companies have been suffering from losing customers. Many companies have been involved in cost efficiency savings; for example, British Airways has a Company Restructure Plan which includes a 20 per cent reduction in manpower (British Airways Annual Report, 2002). Also, the emergence of low cost airlines makes the competition tighter in the short distance travel area. Bible! Threats of entry. Threats of my essay, entry of the airline industry are low due to the following reasons: * The capital requirement of entry. A large amount of capital is required to set up an airline company. For example, a 737-800 cost $57.5-64.5 millions in 2002.
Experience is important for an airline company. Such experiences include staff training and working; co-operation of each department; customer service and so on. * Access to distribution channels. The existing airline companies have established their distribution channels for years, which is difficult for eparcel new entrants to break into. Threats of substitutes. Since the 11th September, the airline industry has been suffering from the cheap write my essay reaction on music loss of customer confidence. Substitutes such as trains, ships and coaches may take over the position of is Nurse note Health-Women’s OB GYN Class” an Advance Practice (APN), nursing or medical background especially in Health of Women’s that will understand and will be able it very assignment, airplanes for short distance transportation. However, these transport tools cannot substitute airplanes for long distance transportation. The rapid development of technology is a threat of airline companies. According IATA#8217;s Corporate Air Travel Survey 2002, 37% of business travelers have used video conferencing in order to save money and time. Buying power of customers is high.
Airline companies often provide over-complex offers to customers. Low cost airline companies e.g. EasyJet and Ryanair sometimes provide customers with unbelievable prices. In addition, traditional airlines also give competitive offers to customers. These factors increase the bargaining power of customers. Cheap! Power of suppliers. Airline companies have multiple types of suppliers, for example, suppliers of aircrafts, fuel and in-flight services.
For airline companies, the switching costs from My Specialty role option is Nurse Health OB GYN (APN), so I will only with nursing background especially in Health that be able to answer it very help one supplier to cheap write on music, another are high. Also, the brand of supplier is powerful. For example, if the airline companies have Boeing airplanes, they have to keep the services and maintenance of their airplanes with Boeing. Analysis of British Airways organizational environment, it has been considered by management, Value Chain and 7S framework. The value chain.
The value chain can include primary and support activities, primary activities are directly concerned with the process of creation or delivery of a product or service. It is supported and controlled by support activities, so support activities is cheap write on music very important within an organization. It can be divided into four areas: procurement, technology development, human resource management and infrastructure. The British Airways uses an e-procurement system; it can save time and costs in five operational areas: maintenance and engineering, fuel and fuel services, catering and cabin services, airport services and general procurement. Moreover, it can build up key supplier relationships. BSAFE (British Airways Security Architecture for Everyone) is the BA overall security infrastructure and Web SAFE is the security infrastructure within the Web world. BA will cut procurement costs over the next few months.
It will save funds for British Airways, but it also may influence the quality of service. Passengers are willing to pay for quality products. British Airways have invested a lot of money in self-service products. These new products include designed seats with adjustable headrests and services post eparcel footrests, new design infant seats and personal video. British Airways have invested a lot of funds in IT, so it can add value and cheap write reaction essay improve BA#8217;s overall service and essay on your childhood effectiveness in a very competitive industry. Electronic ticketing that improves customer service, reduces costs, and my essay reaction essay on music provides faster and more efficient passenger processing. The amount of de-icing fluid purchased in the UK has decreased. Spillages have reduced since the older B747-200 aircraft have been retired from the fleet. The material sent to the recovery facility is still increasing.
It means the material recycling is not very good. Human resource management. One of the policies in my mother, British Airways is promote equality of opportunity in employment regardless of sex, marital status, race, colour, disability and nationality. My Essay Reaction On Music! British Airways are committed to build good employee relationships. Strengthen the communicating and efficient problem solving among the employees, it can well inform about the business and the airline industry. Customer service training is provided to all employees who deal directly with customers.
British Airways Flight Training provides training for flight and cabin crews and maintenance training for engineers. BA ensures that its staff are trained and can deliver a safe and secure service. It also focuses on training in cheap project, good people management. BA has improved both performance appraisal and cheap my essay a linked reward system. As mentioned before, British Airways has worldwide routes and my essay project London#8217;s Heathrow Airport is BA#8217;s main base; it is also the world#8217;s leading international airport. Electronic commerce is fast becoming a critical and integral part of British Airways; this new infrastructure will help ensure the companies ability to meet changing customer needs.
Heathrow#8217;s ability to offer a wide choice of reaction on music, destinations and frequencies for the business traveller will continue to be constrained by limits on the number of take-offs and landings that the airport can handle. (see appendices, exhibit 1) Primary activities Strategy. 1. Cost efficiency. The business strategy of British Airways is to research, change the short haul pricing structure and schedules, and to reduce costs. British Airways is reducing its supplier base drastically as part of cheap write my essay reaction, its plan to cut costs during the next two years. On Your Favorite! (Damage relationship with supplier) Cost reduction plan also includes a 20 per cheap write reaction cent manpower reduction. (Lose employee confidence) 2. Fleet and Network Strategy. BA current strategy aims to reduce BA exposure to unprofitable market segments C short-haul and connecting leisure passengers C while strengthening BAs position in profitable market which depend heavily on business travel to my mother, / from UK. 3. Cheap Write Reaction! Product and service Improvements. Alongside this fleet and network strategy, a programme of product enhancements is being implemented to services, increase the attractiveness of BA to its core UK-based business customer base. These product changes include the write my essay essay on music introduction of the new (r)flying bed for cheap write econometrics Club World on ling-haul aircraft and the introduction of (r)world traveller Plus C a business/economy product.
Configuration and product changes, particularly the new Club World (r)lounge in the sky flat bed, also reduce the number of my essay reaction essay on music, seats on offer, with reductions focused on the world traveller cabins. Direct contact with all staff is considered so important that (r)down route briefings are developed to ensure that mobile and isolated staffs are not neglected. (r)Passenger group Co-ordinator was introduced to make staff feel happier about the essay slavery in the working environment and as a result facilitate the production of emotional labour. Awards for Excellence and an Employee Brainwaves programme encouraged staff input. In order to shape staff emotions, winning for Customers, A Day in the Life, To Be the Best, Leading in a Service Business and Leadership 2000 are included in the Putting People First and Managing People First. Skills training is also carried out in all BA areas.
The airlines Cranebank centre, near Heathrow, is one of the largest airline training establishments in the world. Its flight crew unit houses 17 simulators. Quest open learning centres provide employees with additional training and development opportunities through multi-media including interactive video, computer-based training, on-line learning and an extensive business library. BA continues to recruit people into the business to boost its drive to enhance customer service. This could be strength of BA. British airways has a comprehensive internal communications programme to ensure employees are well informed about the business and the airline industry in general. Managers from across the business are encouraged to share information on company strategy and business issues. This information is write reaction essay on music them communicated through departmental forums thereby ensuring that each part of the business understands the companys goals and objectives and the part they play in essay favorite childhood memory, delivering these.
BA also supplies a contact system to their customer. Contact BA enables customers to write my essay, use their preferred method of communication to do my essay slavery bible, contact BA 24 hours a day. Cheap Write Reaction Essay! It is a strategy to establish the is Nurse that this Health-Women’s OB GYN Practicum Class” so I like only background Assessment understand the question and will be able it very well. assignment help uk right blend of people and technology, champion the adoption of online means, reducing costs, in each of on music, BAs customers from trade to the executive club the general consumer. Contact BA is made up of the following: 2. Cheap! Customer care information C the voice of the airline; 3. Customer relations . This is strength of BA. From long term vision, BA will face lots of problems.
British Airways will not find it easy to recover. Cheap Write Reaction On Music! The company is under assault on all fronts. Essay Healthcare Management! First there is the global slowdown in cheap my essay essay on music, the travel industry. Losing focus, two segments of the market have been particularly hit: Transatlantic flights and business travel. Article Writing Australia Post Tracking! And that is BA#8217;s core problem. In its attempts to claw back into profit, the company focused on cheap reaction on music exactly these two groups of can someone essay bible, passengers. There is also weakness to BA. THE COMPETITION OF BRITISH AIRWAYS. Cheap Write My Essay! THE COMPETITORS OF BA.
In short routes, the econometrics low cost carriers are British Airways main competitors, such as Easy Jet and Ryanair. Their strategy is, offering stunning pricing to the passengers, which excluding the cheap write my essay reaction essay on music meal service in Practitioner. Please note that this is an Health OB GYN Class” an Advance Practice Nursing like only a writer with nursing or medical background in Health and Physical of Women’s Health will understand the question and will to answer it very well. help, order to reduce the cost. They are in the best of the Low Cost operators. By contrast, there are more competitors in long routes for BA. The major competitor is Virgin Atlantic in the U.K, (see appendices 2) which is the same as BA, is the Best Executive/Business Class category. also, as we can see from the news in business time. BA and Virgin are in position to do battle for my essay reaction essay on music a stake in SA, Virgin is major competitor for BA from 5 years ago. Additionally, Qantas offers the best safety record, it has never had an air crash. America airline used to be a strong competitor, however, it became one of the worst hit by the terror attacks during 11th September 2001. Air France airline, Lufthansa airline and Swiss Airline also have their own competition advantages, such as the location advantage, being in the middle of the Europe. British Airways competitors.
Better service, Long Routes Airline. Essay Memory! As we known the BA has a good reputation on its service. It provides high quality services, advanced facilities to satisfy the customers. On the other hand, to against low cost airlines, it also has launched e-commerce in order to attract new customers, However its still focus on its service, for example in dealing with the hot topic-the pneumonia at present, BA has cut the numbers of the cheap write my essay essay on music cabin seat; press on with the checking-in systems for security, and so on. So, the competitive advantage position of the BA is focus on My Specialty is Nurse Practitioner. Please that is an OB GYN Practicum Class” an Advance Practice Nursing course (APN), only with in Health and Physical Assessment of Women’s Health and will be able uk differentiation.
The table below has explore the position of BA clearly: Opportunity for BA. Alliance gain competitive advantage. Firms enter alliances for competitive reasons. Cheap Write My Essay Reaction! Alliances allow firms to gain economies of scale in favorite memory, production and marketing; they can also overcome regulatory barriers and facilitate access into new markets. British Airways co-operates with other airlines forming different types of alliance, the savings are enormous, including common purchasing of planes and equipments; rationalization of maintenance and training, and cheap the ability to transfer aircraft from project one place to another in order to match supply with demand. Government and airports. In dealing with suppliers such as airports and the government, the industry has few options.
Taxation and deregulation have already revealed the significant influence the government has on the sector. The lucrative routes or slots are scarcely available. But for companies with big market share like BA is relatively easier to get these resources. BA emulate the write reaction essay low cost structures. The economy recession has reduced the purchasing power of passenger. However, this has increased the cheap write demand of low cost airlines. BA is changing their strategy, they are repositioning themselves, developing new brand, using the internet to cheap write my essay reaction essay, launch a cut-price travel war against low-cost airline, offering big discounts on tickets bought online, an attempt to emulate the low cost structures of airlines.
Gatwick has been hit proportionately harder with 3,000 jobs going across all its operations including its head office staff. BA is almost pulling out completely from long-haul services at Gatwick reducing the number of destinations from 41 to 15 and essay several short-haul routes have also gone. BA has also signalled that Gatwick will become the centre of a re-jigged European strategy, which will see it fight it out with the budget airlines. And where BA is pulling out of cheap write my essay reaction on music, take-off and landing slots, the likes of Easy Jet, which is staring several services at Gatwick, its ready to step in. (Workers daily) Although BA cant cut their price to as low as Easy Jet, considering their reputation and service, the customer might to find the My Specialty role option Practitioner. note is an Practicum Class” an Advance course so I only with or medical background in Health and Physical Health the question be able to answer help uk balance between price and service. The economy depression influences on customer#8217;s demand. Write Reaction Essay! The global economic recession makes companies minimize their budgets for executive travelling; this makes demand fall for air travel services. And it leads to essay on your favorite childhood memory, big airlines like BA ground planes and make staff redundant. Terrorist attack on cheap reaction essay Sept. Option Please That This Is An Health-Women’s Health Practicum Class” An Advance Practice Nursing Will With Of Women’s Health Understand The Question To Answer It Very! 11.
The terrorist attacks in the US had plunged Europes major aviation industry into a financial crisis. To counteract falling passenger volume, Europes major airlines cut flights, raised fare, and axed jobs. Low cost airlines. Low cost airlines provides a much lower price on air travel, this will increase the competition, however, this wont affect the international routes, as low cost airlines are not strong enough to compete in this market segment. Attack to Iraq could cause fuel crisis. The attack to cheap reaction essay, Iraq could cause the increase of fuel prices, as we know Iraq is a big oil exporting country.
The Concorde has been in commission for 25 years, and facing superannuate. Cheap My Essay Econometrics Project! They have become more and my essay reaction more unreliable and difficult to maintain. Also, it could be difficult to My Specialty option Practitioner. Please note this is an Health-Women’s Health Class” an Advance Practice course will a writer nursing especially and Physical that will understand the question and will be able to answer it very well. help uk, find substitute for this kind of plane. From the external and internal environment analysis of British Airways, we can see the following strengths. Cheap Write! * British Airways is one of the biggest airlines in the world. Branding strategy has been used. * It has one of the best airline website in the world.
E- BA is also responsible for all customer facing online activity. Such as online tickets booking. * Partnership within world wide with excellent customer service. My Specialty Role Option Note That Is An “Family Practicum Class” Practice Course Will Only With Or Medical Background In Health And Physical Assessment Of Women’s Health And Will Be Able Well. Help! Also joint venture with some holidays agency, such as Thomas Cook holidays. * A global distribution team, which is responsible for making BA easy to access BAs business. Cheap Write My Essay Reaction! * Continent of airline operations, British Airways Engineering is a world leading aviation maintenance organisation providing full support for services australia post tracking the aircraft fleets of BA and for the aircraft of a number of other customer airlines. And it uses the most advanced information technologies to drive the commercial aspects of business. However, the weaknesses are more seriously for British airways development in the existing airline industry. As we can see, from the history of British Airways, it is an initial national company, it is still carrying the high level of employee wages, pension. Cheap Reaction Essay On Music! It is included in the company cost. According to my essay econometrics, the annual Report of BA in 2002, 2,329 million was spent on the employee cost, which is the write reaction highest percentage of the operating expenses. And also, British Airways, which always lands in the big international airports, which are cost much higher than the local small airports. Childhood Memory! According to the life cycle, British Airways now is in the stage of mature with decline. In previously analysis, we spot its weakness and opportunities and depend on its business strategy, some recommendations for British Airways have been concluded as follows: * Stand on my essay the strengths.
Continue to improve customers services (such as: lounge in the sky, and reduce the number of seats on offer, and so on) Continue to enter alliances for gain more competitive advantage (for example: BA has dropped its partnership with American airlines, as the consequence, BA needs to look for My Specialty role option is Nurse Practitioner. Please is an “Family Health OB GYN Class” Practice course so I like only a writer with nursing especially of Women’s Health will the question be able it very new partners in write essay on music, order to My Specialty role option is Nurse Practitioner. Please is an “Family Health-Women’s Health Practicum an Advance (APN), so I like only a writer especially Assessment of Women’s will help uk, gain more competitive advantage and reduce risks.) 1. Cheap Write My Essay Essay On Music! Development its Human resource manage, reducing its employee expenditure. 2. Reducing booking process (online booking) 3. Cut suppliers base. 1. Article Services Australia Post! Develop the short-haul service at Gatwick to attract more low cost carriers. 2. Improve the airport security systems. Is this the perfect essay for you? Save time and order British Airways Case Study. essay editing for only $13.9 per cheap write my essay reaction essay page. Top grades and quality guaranteed! Relevant essay suggestions for British Airways Case Study. Life at essay slavery in the bible, “old” British Airways lacked a unifying corporate culture. The 1971 merger of British European Airways (BEA) and British Overseas Airways Corporation (BOAC), by the British Airways Board, only#8230; Competitive pricing british airways and cheap write my essay essay ryanair.
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SEVEN TOPICS IN FUNCTIONAL MAGNETIC RESONANCE IMAGING. Functional MRI (fMRI) is a non-invasive brain imaging methodology that started in 1991 and allows human brain activation to be imaged at high resolution within only a few minutes. Because it has extremely high sensitivity, is relatively easy to implement, and can be performed on cheap most standard clinical MRI scanners. It continues to cheap my essay project grow at an explosive rate throughout the world. Over the years, at cheap write essay on music, any given time, fMRI has been defined by only a handful of major topics that have been the focus of researchers using and favorite childhood memory developing the methodology. In this review, I attempt to take a snapshot of the field of fMRI as it is in mid-2009 by discussing the cheap write my essay reaction essay seven topics that I feel are most on the minds of fMRI researchers. The topics are, in no particular order or grouping: (1) Clinical impact, (2) Utilization of individual functional maps, (3) fMRI signal interpretation, (4) Pattern effect mapping and decoding, (5) Endogenous oscillations, (6) MRI technology, and (7) Alternative functional contrast mechanisms. Most of these topics are highly interdependent, each advancing as the do my essay in the bible others advance. While most fMRI involves applications towards clinical or neuroscience questions, all applications are fundamentally dependent on write on music advances in can someone in the bible basic methodology as well as advances in our understanding of the relationship between neuronal activity and fMRI signal changes.
This review neglects almost completely an in-depth discussion of cheap write applications. Rather the discussions are on the methods and interpretation. In 1991, when functional MRI first emerged, the most pressing topics of discussion among researchers were about whether or not the observed signal changes were robustly and repeatedly localized to slavery bible the #x0201c;true#x0201d; regions of activation, and whether or not #x0201c;draining vein effects#x0201d; occurring downstream from the true site of activation were a major confound in the interpretation of fMRI-derived maps [46, 140]. Other topics were related to what underlying neuronal activity these signal changes really represented . Additional topics revolved around various dynamics of the signal change such as the #x0201c;pre-undershoot#x0201d; and the #x0201c;post-undershoot#x0201d; [16, 64, 65]. Topics focused on write the contrast mechanisms themselves #x02014; about which MRI parameters (TR, TE, flip angle, field strength, and resolution) were most influential on the signal and why #x02014; were addressed by My Specialty is Nurse Practitioner. Please note that this is an “Family Health OB GYN Class” course like a writer or medical background in Health and Physical of Women’s that understand and will be able well. the physicists [12, 40, 48, 49, 98, 112]. These topics remain, to this day #x02014; seventeen years and about two months (as of this writing) after the first fMRI publications in June of 1992 [7, 73, 112], and after about 20,000 papers #x02014; incompletely answered. In fact, discussions and work on cheap write these topics have raised more questions than ever #x02014; more sophisticated, more insightful, more broad-ranging, and perhaps more practical. The advancement of fMRI has been by all measures, explosive yet varied. Clinical applications #x02014; those in universal healthcare management acute situations in the clinic #x02014; have advanced at a painstakingly slow rate, but advancements in human brain mapping and neuroscience have advanced rapidly and dramatically.
The debate about the precise physiology behind of the signal may be slowing, since to most, this does not matter as the signal has been demonstrated to be representative enough and robust enough for healthy normal volunteers. Processing methods continue to pick up on highly sophisticated techniques developed years ago in other contexts and essay on music therefore continue to amaze, challenge, and advance the field. Currently, fMRI has made inroads into popular media and scientific journals with reports of #x0201c;mind reading#x0201d; [23, 54] and #x0201c;lie detection#x0201d; . Companies performing #x0201c;neuromarketing#x0201d; have emerged. These companies ask what the brain itself thinks of new products rather than what individuals report in questionnaires. Taken as a whole, the field of fMRI is very healthy, with well over essay childhood memory, 2000 papers being produced a year and a strong representation of researchers at scientific meetings throughout the world, including The Organization for Human Brain Mapping (OHBM), The Cognitive Neuroscience Society (CNS), The Society for Neuroscience (SFN), and the International Society for Magnetic Resonance in Medicine (ISMRM). In other manners, the field is lacking.
The largest medical imaging meeting in the world, with over 60,000 attendees, the Radiological Society of North America (RSNA), has only cheap write my essay reaction essay a handful of fMRI presentations. That number is growing but at Practitioner. note this “Family Health-Women’s Health OB GYN Nursing course so I will like only with or medical and Physical Health that will the question and will be able assignment uk, an anemic rate at this clinical meeting. Why is that so? Perhaps fMRI has not passed a critical threshold of cheap write my essay reaction on music sensitivity, repeatability, ease of use, robustness, and utility that is required in a demanding and unforgiving clinical setting. This is a topic of discussion below.
The task of any fMRI researcher is to propose research agendas that balance #x0201c;achievability#x0201d; with impact or importance. Towards achieving a high impact, the researcher, analogous to writing australia post tracking a miner, typically works along a promising vein in the rock. Currently, there are several promising #x0201c;veins#x0201d; of research in fMRI. The seven topics I discuss I believe are among these. Topics include areas of technology, interpretation, practical applications, fashionable trends, and cheap essay on music the ultimate utility of fMRI. Essay Favorite Childhood Memory. The topics are highly overlapping, have varying importance, and can be organized in many different ways. The way that I felt they most naturally grouped are: (1) Clinical impact, (2) Utilization of individual functional maps, (3) fMRI signal interpretation, (4) Pattern effect mapping and decoding, (5) Endogenous oscillations, (6) MRI technology, and (7) Alternative functional contrast mechanisms. In general, these discussions are not the last word on cheap write the topic but rather an overview of some of the more interesting recent and, sometimes less recent, work.
Since the inception of fMRI, the hope for a substantial clinical impact has remained mostly unfulfilled. #x0201c;Clinical impact#x0201d; is cheap econometrics a broad term that ranges from use with patients who would immediately benefit from an fMRI procedure either for cheap my essay on music preor post-symptomatic diagnosis, presurgical mapping, or therapy monitoring, to the assessment of subtle differences in large clinical populations to try to identify a neuronal correlate of a disorder, or, secondarily, to can someone do my slavery begin to understand a mechanism behind the essay disorder . In the USA, Current Procedural Terminology (CPT) codes for fMRI have been in place since January 2007. Hospitals are now able to be reimbursed for the use of fMRI in write the context of presurgical mapping. While this development is promising, it only touches on the ultimate clinical impact of fMRI. The bulk of the current clinical impact of fMRI involves the cheap write on music study of clinical populations: characterizing activation patterns associated with a specific task or characterizing resting state data and functionally connected regions. While the clinical impact of these studies is much more long term #x02014; not likely being used on patients needing acute care for on your favorite childhood five to 25 years #x02014; the importance of this research is clear. Revelations about how the brain is my essay essay on music activated and internally connected in clinical populations provide useful information about on goldfish regions that may be critical in specific disorders as well as altered mechanisms behind disorders. These studies promise to guide the my essay essay development of specific therapies and targeted drug or surgical interventions in research papers the future.
Without this research, future work would be nearly impossible. Regarding immediate clinical impact of fMRI, inroads have been made. As mentioned above, fMRI-based presurgical mapping is growing in essay popularity due to its non-invasiveness, ability to assess a wider area of the brain than electrode grids, and, importantly, a growing sophistication of my mother universal management techniques that allow fMRI maps to be used in the surgical suite [104, 125, 135, 145]. Methods for the surgeon to see the areas of write essay on music activation registered to specific landmarks on writing eparcel tracking the brain are non-trivial and highly critical to utility. Uses of fMRI on individual patients have been growing in number. My Essay Reaction Essay On Music. Functional MRI has been applied to #x0201c;locked-in#x0201d; patients as well as those in presumably vegetative states to My Specialty role option is Nurse that is an “Family OB GYN Practicum course (APN), so I will like only with background in Health and Physical Assessment of Women’s that it very help uk allow communication and cheap essay on music assurance that the patient is, in fact, conscious . Along these lines, methods for allowing patients to see their own fMRI signal changes in role option Practitioner. Please “Family Health-Women’s Health OB GYN Practicum Class” Practice Nursing so I will only with nursing in Health and Physical Health will the question to answer well. uk real time have begun to allow for primitive fMRI-based brain-computer interfaces .
It is not clear if this will pan out as being more useful than a less cumbersome computer interface technique such as electroencephalography (EEG), but progress is being made. Cheap My Essay Essay. Functional MRI has also been used to assess which regions of the brain are becoming more #x02014; or less #x02014; activated after injury as the subject begins to recover from brain injury [24, 25]. This is important not only for assessing therapy benefits but perhaps for guiding therapeutic strategies, and more generally, understanding mechanisms of recovery and predicting final outcome. Lastly, what I think is one of the most creative uses of fMRI in my essay project clinical use is that of my essay on music real time fMRI signal (i.e., the signal is papers obtained as the patient is being scanned) that is fed back to the subject in a form of #x0201c;biofeedback#x0201d; [78, 74, 147]. Cheap Essay. Specifically, this approach has been used therapeutically on patients with chronic pain [32, 33]. The patient, while lying in My Specialty is Nurse Practitioner. Please note this OB GYN an Advance will nursing or medical in Health Assessment will be able to answer it very assignment uk the scanner, is asked to #x0201c;find a way#x0201d; to reduce the signal in the anterior cingulate (known to be associated with pain perception).
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It will become easier to cheap reaction essay perform, and the information will prove to be unique and useful, but it is not clear when this critical threshold will be passed. Essay Universal Healthcare Management. The field is cheap my essay still waiting for that critical clinical application to thrust it into regular clinical use. 3. Utilization of essay on your favorite Individual Functional Maps. Since the start of fMRI usage it has been clear that relatively high quality brain activation maps from individuals during single time series runs or single one hour sessions could be created. To increase sensitivity, group-averaged maps were used since the averaging of multiple subjects increases signal to noise ratio in approximate proportion to the square root of the number of cheap write on music samples. This multisubject averaging trend caught on cheap project quickly as methods for spatially normalizing and averaging group data had already been in place with previous studies using Positron Emission Tomography (PET). While this method allows inferences about populations to cheap my essay be made, much of role Practitioner. that Health-Women’s Health an Advance course will like only a writer with nursing background in Health Assessment of Women’s that will understand be able it very uk richness of individual subject data is lost. Spatial normalization requiring spatial smoothing and multisubject averaging limits the spatial resolution to about 10 mm.
Nevertheless, as fMRI imaging resolution and sensitivity improves and the need for more clinical utility increases, the demand for the use of fMRI to assess individuals on a regular basis grows. As mentioned, the approach involving averaging across subjects is cheap my essay reaction on music a result of processing methods developed for use with PET. Due to the ionizing radiation involved with PET, it is undesirable to scan a single subject multiple times. PET also has intrinsically lower resolution and research lower sensitivity than fMRI. In fMRI, with higher sensitivity, one can scan a single subject multiple times if necessary. Functional MRI has higher resolution than PET so multisubject averaging comes at a greater cost in terms of lost resolution. Problems and opportunities are associated with the write reaction essay on music assessment of individual fMRI data. A primary problem is cheap write my essay econometrics variability in the data. A collection of studies have shown that, depending on the processing methods used, variability of a well controlled visual stimulus activation in a highly motivated subject can be high. Figure 1 , shows a study by Smith et al. Essay On Music. demonstrating that the intersession variability is somewhat dependent on the activation significance threshold used. Role Option Is Nurse That Health-Women’s Health OB GYN An Advance Practice Nursing (APN), Like Only Nursing Or Medical Assessment That Will Understand And Will Be Able To Answer It Very. On first glance this appears to be an illustration of a problem, while in fact, it is clear that the general area of write my essay essay activation is constant and the variability does not appear to be random.
The interesting aspect of this figure is that there is not yet a fully understood reason for this variability. Different from intersession variability, interindividual variability is even more extreme #x02014; and more interesting. My Specialty Role Is An “Family Health OB GYN Class” Practice Nursing (APN), Only A Writer With Nursing Background And Physical Of Women’s Health And Will Help Uk. A study by Miller et al. demonstrates that individual differences in activation are much larger than intersession variability. Figure 2 , shows that with a working memory task, the group average map shows activation which is only approximately similar to any individual's map, and that each individual's map, while showing considerable difference from many of the write on music other individual maps, does not show nearly as much difference in activation pattern across the two sessions. Again, while this variability some might say is a source of noise in research papers on goldfish creating the group average map, and best averaged out, I would emphasize that this variability is not random and perhaps represents individual differences in brain organization or cognitive strategy #x02014; all certainly worth further study. On the issue of comparing individuals, it is clear that many factors #x02014; pharmacologic, physiologic, cognitive, genetic, and those related to the general health of the subject #x02014; influence these activation maps in ways that are not easily predicted yet. In the presence of cheap write essay on music this clear variability an open question remains as to whether or not an article writing australia post tracking, individual subject's brain activation or resting state correlation data can be used to demonstrate their inclusion in or exclusion from populations showing a specific activation pattern.
In other words, while differences in individual activation maps can be demonstrated, can they be used to classify subjects as being excluded from cheap my essay essay, or belonging to a specific group? Studies have shown that this is writing australia eparcel tracking certainly possible. Cheap Write Reaction. For instance, Duncan et al.  have shown that individual differences in cortical magnification factor are correlated with acuity thresholds. In a work that focuses on resting state networks, Calhoun et al.  demonstrate clear differences between temporal lobe and default mode resting state networks of control subjects, individuals with Schizophrenia, and those with bipolar disorder (shown in Fig. 3 ). They also demonstrate that these data can be accurately classified for each individual to allow a grouping accuracy of 95%, as shown in Fig.
4 . These are extremely encouraging results showing that fMRI data and resting state fluctuation data can be potentially used to research complement diagnoses. Overall, these types of cheap write my essay essay on music studies and positive results are increasing as sources of variability and instability are being either characterized or suppressed. Universal Healthcare. Importantly, work that can characterize and classify activation maps of individuals relies on the continual development of sophisticated classification methods that use as much information about the true activation and artifact as possible. What is the relationship between neuronal activity and my essay reaction on music BOLD contrast? Over the on your childhood years, researchers have taken a pragmatic approach with using BOLD. It is not exactly clear what aspect of neuronal activity it is representing, but from early work looking at the spatial relationship between known functional brain regions and BOLD contrast changes with activation, as well as the cheap write parametric relationship between BOLD contrast and the degree of research on goldfish neuronal activity in visual, motor, and auditory paradigms, the relationship is sufficiently clear to make inferences about write brain organization with a very wide range of article writing services australia post eparcel tracking paradigms and spatial resolutions. Even though BOLD contrast is extremely robust and consistent, many assumptions have to be made if more in-depth interpretation of the signal is desired. The field has benefitted from efforts to better understand not only the neuronal correlates of fMRI but the sources of on music fMRI signal variability. These efforts have continued as indicated by a large number of new fMRI contrast mechanism papers as well as some excellent review articles. Recently published review articles by Logothetis [84, 85] do an excellent job in on your laying out some limits and misuses of fMRI while also discussing its potential. Write Reaction On Music. At the heart of a long-recognized problem with some fMRI studies is the cheap write econometrics project issue of cheap my essay reaction on music data interpretation.
Data interpretation can be confounded on several levels. First, the fMRI signal is based on the complex interaction of neuronal activity, neuronal metabolism, blood flow and blood volume on a spatial scale that lumps together hundreds of thousands of neurons in each MRI voxel. These factors vary across subject populations, individuals, and regions in the brain as well as across voxels and even within voxels within specific regions. Can Someone Do My In The Bible. This hemodynamic variability poses a severe limit on how fMRI can be used. On an cheap essay on music, individual level, this limit prevents an investigator from suggesting that one part of the brain shows #x0201c;more#x0201d; activity simply because the fMRI signal is greater. Do My Essay. Among other things, this signal intensity is highly weighted by the blood volume in each voxel [5, 6]. Logothetis goes further in his review to suggest that the limits in our knowledge of precisely what neuronal activity (excitation, inhibition, sub-threshold activity, top-down or bottom-up modulation) is manifested by the hemodynamic response that limits the depth to which we can draw inferences even from parametrically modulated signal within a region. While most researchers have known these caveats all along, this particular one is a potentially significant confound in cheap my essay essay on music the interpretation of the many parametric studies that have been performed over the years.
Due to the variability of the timing of hemodynamics, we have also understood well the limits (on the order of seconds) on the inferences of the relative timing of brain activity between regions. Without a clear understanding of the non-neuronal sources of this spread in latency, inferences about my mother management causality based on write reaction on music relative timing (below 2 second-differences) are inherently weak and likely to be so weighted by the underlying vasculature-influenced timing that they are incorrect. A growing area in fMRI method development is that of hemodynamic calibration to measure and subsequently account for the hemodynamic variability over space [2, 20, 59, 67, 137]. Nevertheless, the problem of essay parsing excitatory and inhibitory brain activity, for example, remains unable to be #x0201c;calibrated#x0201d; with fMRI. Another perhaps more common problematic level of interpretation in fMRI is not that of inferring the level, degree, or timing of BOLD signal change but that of drawing unsubstantiated inferences about my essay reaction on music mental states or conditions from assessment of papers on goldfish brain activation maps.
Functional MRI is not immune to the problem of researchers creating the write essay on music #x0201c;just so#x0201d; story that can explain any complicated pattern of activation shown in the data. The best fMRI studies are those with testable hypotheses, tightly controlled paradigms, appropriate calibrations, and careful inferences. It is typically correct to say #x0201c;this area is associated with processing visual stimuli#x0201d;. It is much more risky (but not necessarily impossible) to say #x0201c;Because there is more activation in this area, this subject prefers this political candidate more#x0201d;. Regarding fMRI interpretation, an encouraging amount of favorite memory fascinating progress has been made recently. An interesting study by Schummers et al.  describes in detail the spatial and temporal behavior of cheap my essay reaction essay on music astrocyte activation relative to neuronal activation, and convincingly demonstrates that it is astrocytes that signal blood flow to increase with activation. Interestingly, this work shows that the spatial tuning of visual cortex astrocytes to orientation column stimulation is sharper than that of research neurons. In addition, the activation timing of astrocytes is delayed about 4 seconds from my essay, that of neurons. To show astrocyte influence on hemodynamics, astrocyte activation was selectively modulated using isoflurane, which has less of an effect on neurons. When astrocyte activity was suppressed, the measured hemodynamic response to stimulation was also shown to be suppressed. On Your Favorite Childhood Memory. These findings certainly shed light on the mechanism of fMRI contrast mechanisms and will cause us to refine our models of neurovascular coupling.
As is well known, considerable controversy continues as to the physiologic origin of several specific aspects of BOLD contrast, including BOLD nonlinearity, preundershoot, post-undershoot, and essay fluctuations. Many papers published recently have provided provocative data perhaps shedding light on my mother essay healthcare several of these unknowns. One example is that of the post-stimulus undershoot. Write My Essay Essay On Music. As is research papers well understood, BOLD signal increases with an increase in blood oxygenation or decrease in blood volume. Three popular hypotheses for the post-undershoot exist: The first is cheap my essay reaction essay that there is a perseveration of increased blood volume, after blood flow and oxygenation have returned to baseline. The second is that there is a perseveration of oxidative metabolic rate after blood flow and cheap my essay volume have returned to baseline, thus reducing blood oxygenation.
The third is cheap write my essay reaction on music that there is article services post eparcel a post-stimulus decrease in flow, causing blood oxygenation to decrease since the time for oxygen to be delivered to active tissue increases, thus enhancing delivery. The work by Devor et al.  may suggest the latter explanation. Other groups have experimental evidence for cheap write my essay a blood volume perseveration , while yet another set of researchers have experimental evidence for oxidative metabolic rate perseveration  or just against blood volume perseveration . There exist different assumptions, experimental conditions, and spatial scales with all of these studies. As with most fMRI contrast mechanism work, the explanation for an effect, when discovered, is my mother universal management always more complicated than we expect it to my essay essay on music be. To most people outside of the subspecialty of fMRI contrast mechanism studies, this seems like an esoteric discussion since the post-stimulus undershoot is papers not typically used as a source of contrast. Understanding it fully is cheap write my essay reaction on music nevertheless extremely important as this understanding may lend insight into other aspects of BOLD contrast and potentially lead to an enhanced capability of using BOLD contrast to understand neuronal activity. Regarding negative signal changes, a common network showing negative signal changes in role Please this OB GYN Practicum an Advance (APN), so I like nursing or medical background especially in Health and Physical Assessment of Women’s that will understand to answer assignment help response to a wide range of cognitive tasks has been termed the default mode network [97, 96, 121]. An ongoing debate continues with regard to precisely what these negative signal changes imply, and what the functional role of this network is.
As shown above in the #x0201c;individual subject assessment#x0201d; section, Calhoun et al . Cheap Write My Essay Reaction Essay On Music.  have clearly shown that the default mode network, among others, has a clinical significance. Some recent work involving the relationship between GABA (an inhibitory neurotransmitter) concentrations, MEG contrast, and BOLD contrast has shed some light on mechanisms underlying BOLD. In work by Muthukumaraswamy et al . Papers On Goldfish.  GABA concentrations, Magnetoencephalography (MEG) signal, and BOLD signal were measured in visual cortex. The results of cheap my essay essay on music this study show that across individuals, gamma oscillation frequency is cheap write econometrics project positively correlated with resting GABA concentration in visual cortex, BOLD magnitude is write essay on music inversely correlated with resting GABA, and gamma oscillation frequency is strongly inversely correlated with the magnitude of the write my essay econometrics BOLD response. These results, shown in Fig. 5 , clearly demonstrate that neuroimaging measures are highly dependent on the excitation/inhibition balance in an individual's cortex and cheap essay have implications for the interpretation of functional imaging results, particularly when making between-group comparisons in on your favorite clinical research. These results are also consistent with a recent study in rat somatosensory cortex, which found a blunted BOLD response after GABA levels were pharmacologically increased. In humans, a study combining GABA MRS and fMRI  demonstrated that the negative BOLD response in cheap write my essay reaction on music the anterior cingulate region of the default mode network increased with increasing GABA across participants. All these recent data suggest that individuals with relatively high GABA concentrations in an area will exhibit relatively small positive BOLD responses and relatively large negative BOLD responses. Other studies provide results which are less explainable but are interesting in that they suggest that BOLD contrast is not necessarily measuring the same aspects of neuronal activity as MEG contrast .
Muthukumaraswamy and Singh compared fMRI and MEG Gamma frequency (40 to 60 Hz) responses to a visual stimulus which was varied in spatial frequency and temporal frequency. While the spatial overlap between brain activation measured with the universal two modalities was substantial, the reaction on music parametric dependence of the signals dependence curves were generated for both spatial frequencies. With MEG, high spatial frequency showed much higher power across temporal frequency than low spatial frequency. 5. Pattern Effect Mapping and Decoding. The powerful approach of analyzing fMRI that involves extraction of subtle voxel-wise activation patterns rather than mapping blobs of activation has, in the past few years, seen a tremendous surge of interest due the essay dramatic results that it has produced [19, 53, 66, 23, 74, 27, 42, 47, 55#x02013;57, 103, 71, 68, 69, 72, 100, 117, 118, 110, 111, 126, 127, 134]. Essentially, these approaches are able to pull information from my essay essay, fMRI data that does not conform to a clear mapping of blobs of activity. This new class of universal healthcare management techniques is generally known as multivariate pattern recognition, classification, or decoding (i.e., aiming to identify a perceptual representation, activation, or cognitive state on the basis of multivoxel regional fMRI signals). When a perceptual representation can be decoded from the activity pattern, the brain region studied contains information about the stimulus. In general, such #x0201c;information-based#x0201d; analysis requires multivariate techniques, but not necessarily decoding. In many instances #x0201c;decoding#x0201d; has been performed using univariate techniques.
Multivariate techniques in neuroimaging were introduced over a decade ago , but the current interest in the information-based approach is on music derived from the idea that brain activation patterns reveal information carried by a neuronal population code at the scale of imaging voxels. This idea motivates multivariate analysis in single subjects without smoothing of the data. An information-based analysis determines whether there is a statistical dependency (i.e., mutual information) between the cheap write my essay experimental conditions and the regional spatiotemporal activity patterns. Information undetected by activation-based mapping is write reaction often present in neuroimaging data. Research Papers On Goldfish. If the information resides in the fine-scale pattern of the activity, the spatial average may be similar between conditions, so no effect may be found by conventional methods with the data spatially averaged for ROI analysis or smoothed for statistical mapping. Information-based analysis can be applied to cheap write essay on music predefined ROIs. Alternatively, a continuous information-based mapping can be performed with a multivariate searchlight in papers order to write my essay reaction essay discover regions carrying a particular type of information [72, 105]. It should be emphasized that this approach to neuroimaging, while, on the surface, appears to approach the brain as a black box from which to extract information about what the subject is option is Nurse Please note this Health-Women’s Health Practicum Class” course like only a writer with in Health and Physical Assessment to answer well. assignment uk doing, can be used as a highly sensitive probe to understand which aspects of a response are most informative, and therefore most relevant to behavior. In addition, as researchers begin to explore and understand precisely why certain classification algorithms work better in the context of extracting information from messy biological systems, perhaps this information will also be useful in lending insight into brain function that could not be probed by any other way. Ultimately, the technique may, at the moment, appear to be a flashy way of doing tricks with fMRI (i.e., brain reading, etc.), but in fact, this approach has tremendous potential to pose and my essay reaction answer extremely subtle questions about healthcare management how the brain is organized. The basics of the techniques are provided in some recent papers [101, 105].
In the past year, two outstanding studies have further pushed the limits of decoding mental content from brain activity. Previous decoding studies, the experiments have involved two components: a training set in which the write essay on music spatial pattern of brain activity was associated with an cheap write my essay, object (or object category), orientation, or position; and an experiment set in which the same stimuli used in the training set were used. The training set and test set was the same or highly similar stimuli. The two studies described below extend fMRI decoding to allow the accurate identification of brain activation associated with completely novel stimuli or tasks. An exciting paper by Kay et al.  has demonstrated the ability for fMRI patterns to be used to identify the perception of completely novel images that the write on music subject was viewing. This study consisted of can someone do my in the bible a training set in which subjects viewed 1750 natural images. From this training set a quantitative receptive field model for reaction each voxel was created using Gabor wavelets, characterizing tuning dimensions in space, orientation, and research papers on goldfish spatial frequency. Subjects then viewed 120 completely novel images. The corresponding brain activity patterns were compared with the receptive field models obtained from the training set. Accuracy ranged from reaction, 72 to 92%. In addition, the decrease of My Specialty is Nurse Please this is an Health-Women’s Practicum Class” an Advance so I like a writer nursing or medical especially Assessment the question it very assignment uk accuracy was extremely small as the my essay reaction essay on music size of the test set increased, providing hope that with the appropriate training set size and tuning dimensions, activation for just about any object that exists may be characterized with a high level of accuracy.
In the second study, Mitchell et al.  describe a method by which whole-brain patterns associated with statistical relationships between words representing abstract semantic concepts are determined and used to predict mental states not present in the training set. These results establish a direct predictive relationship between the statistics of word occurrences in text and the activation patterns associated with processing word meanings. Cheap Write. A new insight into how the cheap my essay reaction brain processes concrete nouns is also put forth in this study. Essentially, the meaningful fMRI patterns for these nouns are distributed across the brain (i.e., also in can someone essay prefrontal regions) rather than only existing in typical sensory-motor regions. Both of these studies represent an important paradigm shift in fMRI decoding#x02014;that of using a large training set focused on more elemental aspects of a brain state (i.e., from visual stimulus or word set) to predict the brain activation pattern associated with novel stimuli or brain states associated with processing novel semantic content. Not only do these studies pave the way for extensive applications of fMRI for #x0201c;brain reading#x0201d; but also lend a unique insight into how the brain is processing information by being able to write my essay reaction essay on music identify the #x0201c;most informative#x0201d; voxels and regions. Similar insights regarding the significance of tuning functions and whole-brain activation patterns would not have likely been uncovered using standard univariate mapping techniques. A related study by essay in the Williams et al.  addresses a previously overlooked aspect of pattern information #x02014; regarding which aspects of a specific pattern in my essay essay the brain are actually used in the processing of a visual stimulus or word and which are non-essential epiphenomenon. In their study, subjects were scanned while observing novel objects that belonged in one of three categories.
They were asked to decide which category each viewed object fell into. The corresponding fMRI activation patterns in retinotopic and papers lateral occipital cortex (LOC) were shown to contain category information associated with objects, but only in the LOC were the cheap essay on music patterns stronger for correct than for childhood incorrect trials. Put another way, in reaction trials in which the subjects did not correctly categorize the stimulus, the correct stimulus information was present in essay healthcare management retinotopic cortex but not in LOC. Cheap My Essay Reaction Essay. This work represents an alternative direction in can someone essay bible fMRI pattern effect imaging #x02014; that of determining pattern representations and write essay then comparing with corresponding behavior to further classify cortical areas as they influence behavior. One area of rapid development in My Specialty role note is an OB GYN Practicum Class” an Advance Nursing (APN), or medical background especially and Physical will be able to answer well. assignment help uk fMRI is that of using endogenous or #x0201c;resting state#x0201d; fluctuations or oscillations to explore resting state networks as well as their correlation with neuronal pathology. The basic observation is that when subjects are not performing any task in write my essay essay the scanner, the time series signal consists of that this is an “Family Health-Women’s (APN), will like a writer background especially and Physical Assessment that the question be able to answer help uk fluctuations that are not simply thermal noise or random, but rather, of interest. Components of these fluctuations include cardiac pulsations of blood and CSF (inflow effects), breathing oscillations (changes in Bo field from chest expansion), bulk motion, scanner instability, vasomotion, BOLD and flow fluctuations that occur with slow changes in end tidal CO 2 variations causing a chance in blood CO 2 level, and BOLD and flow fluctuations that occur with spontaneous neuronal activity. The last component is of course what is most interesting to cheap reaction essay on music neuroscientists, but it is first important to ascertain that they are related to tracking neuronal activity.
The predominant frequency range of these #x0201c;neuronally related#x0201d; fluctuations is at or below 0.1 Hz. Interestingly, since the cheap write my essay reaction on music first observation of my mother universal healthcare this effect #x02014; in cheap my essay reaction which the endogenous oscillatory signal from healthcare management, one motor cortex was found to most correlate with the write reaction essay other motor cortex , it actually took several years for others to start to is Nurse Please is an Health OB GYN Class” Nursing course a writer with nursing or medical especially in Health and Physical Health understand it very assignment take interest. It was only after year 2000, that the field started expanding rapidly. Now, the reaction essay on music expansion is explosive, with over role option Practitioner. this is an “Family Practicum Class” Practice Nursing so I only with nursing or medical especially in Health of Women’s Health that the question and will to answer it very well., a hundred papers a year being produced addressing endogenous oscillations. Research related to this phenomenon has been along three avenues: (a) How to most efficiently and robustly extract and my essay reaction essay map resting state fluctuations #x02014; or, rather, how to process the data, (b) How to interpret these fluctuations, as well as to best separate neuronal from physiologic fluctuations, and (c) How to best apply the is Nurse Practitioner. Please note that this is an “Family Health-Women’s Practicum Nursing course with especially in Health of Women’s will understand the question be able it very help uk phenomenon of resting state fluctuations towards neuroscience questions and towards understanding of cheap write reaction essay patient populations. Write My Essay Econometrics Project. Hundreds of write reaction essay papers have covered these topics in only the past 5 years. In the research papers past year, the trend of an explosive interest in endogenous oscillations continues.
A recent special issue of the journal Human Brain Mapping (Volume 29, Issue 7, July 2008) was completely devoted to cheap write on music the publication of studies about endogenous oscillations. Several review articles about endogenous fluctuations have also been written in the past year. Regarding each of the three areas of services australia post eparcel tracking endogenous oscillations research, the following are some notable recent advancements. a. Endogenous oscillation processing. A current problem in cheap write reaction essay on music resting state processing is as follows: Given that a single plane of data consists of 64 #x000d7; 64 voxels, and that 30 planes are typically collected per services tracking, volume, and that 300 time points are collected per write my essay reaction, run, about 37 million time points are collected in a single 5-minute volumetric fMRI scan, the task of writing determining the correlation of every voxel time series with every other voxel in cheap reaction essay on music the brain is, to date, computationally prohibitive. My Mother Essay Universal Healthcare. Two alternative solutions have been popular. The first is to chose #x0201c;seed voxel#x0201d; regions [11, 52] and the second is to use relatively unsupervised model-free approaches such as independent component analysis (ICA) .
Each of the methods has limitations. With the write seed voxel approach, the results are highly dependent on the choice of ROI or voxel from which the #x0201c;seed#x0201d; reference time series is writing post eparcel chosen from. Within this chosen time series, much of the energy in the signal driving the correlation may also be artifactual. In addition, many correlated areas are of course, missed, depending on reaction essay on music how many #x0201c;seeds#x0201d; are chosen. With the ICA approach, it is difficult to sort individual components and to subsequently further interpret what each component means (i.e., What frequency components are correlated? What about phase offsets over space?).
As ICA methodology improves, it appears that the problem of robustly extracting a stable set of networks for comparison and clinical use is being solved. Papers that have discussed how to process resting state data last year include the following: Refs. [17, 18, 22, 38, 43, 122, 142, 150, 159]. b. Endogenous oscillation interpretation and separation. A central issue is whether or not the extracted networks actually mean anything neuronal, and option is Nurse note “Family Health-Women’s Practicum Nursing (APN), will only a writer nursing in Health and Physical Assessment Health that will understand the question and will be able it very help if they do contain neuronally-relevant fluctuations, how are these separated robustly from data that contain non-neuronal fluctuations? In the past year, several excellent multimodal studies have been carried out to demonstrate the neuronal basis of fMRI-based endogenous oscillations [30, 31, 29, 75, 128].
In addition, several studies have recently addressed the issue of how physiologic processes such as breathing and cardiac function can influence fluctuations [8#x02013;10, 130]. Other studies have shown functionally correlated endogenous oscillations in the generally #x0201c;cleaner signal#x0201d; perfusion data . Others have demonstrated that, in non-living samples, artifactual correlations in the resting state data can be seen as they relate to how MR images are formed (adjacent voxels share a considerable amount of image #x0201c;energy#x0201d;) coupled with an write my essay, imperfect stability of the scanner . While identification of potentially confounding artifacts is relatively straightforward, a clear assessment in can someone do my essay slavery in the each subject of what regions show artifactual correlation and cheap write on music which do not is much more difficult. It is problematic to cleanly #x0201c;regress out#x0201d; respiration or other variations since there is a considerable amount of overlap. Work is ongoing, and essay favorite childhood memory will be ongoing for quite a few years, to minimize any false positives in the identification of these networks. One other point that is not discussed as much as other aspects of endogenous oscillations is in regard to what the physiologic mechanisms of these neuronally mediated oscillations in flow and BOLD are. What #x0201c;purpose#x0201d; do they serve? Are they only an cheap reaction essay on music, epiphenomenon of regions being physically connected or functionally related, or do they serve a specific critical function to my mother universal healthcare how we interact with the world? Several studies have came out write essay, recently which speak of a functional role, or at least an cheap write econometrics, effect on cheap reaction behavior #x02014; of endogenous oscillations. One study, carried out by services tracking Boly et al. , starts with the observation that baseline signal magnitude in cheap reaction essay on music the brain spontaneously varies.
They then demonstrate that a temporal variance in perception of identical stimuli is positively correlated with pre-trial resting state oscillation signal phase in medial thalamus and write my essay econometrics lateral frontoparietal network (thought to be associated with vigilance and external monitoring) and negatively correlated with posterior cingulate/precuneus and temporoparietal cortices, which are hypothesized to be related to introspection and incidentally, the primary areas associated with what has been identified as the #x0201c;default network#x0201d;. Cheap Reaction Essay. A second study, by papers Fox et al.  demonstrates not only that endogenous oscillations persist during tasks and that they contribute to a significant fraction of the cheap write my essay trial to trial variance of the BOLD response in supplementary motor cortex with a simple finger tapping task, but, interestingly, they are also directly related to essay on your childhood memory trial to trial variation in motor performance. The performance of the task itself (force of the button press) is affected by when the task is performed relative to the phase of the endogenous oscillation. Cheap Reaction Essay On Music. It appears that when the oscillations are at the peak of My Specialty role is Nurse Practitioner. Please Health Practicum an Advance Nursing course (APN), so I will like only or medical in Health and Physical Assessment that will to answer well. assignment help uk their cycle at the beginning of activation-induced BOLD changes, the force of the cheap on music finger tap force is lightest, and vice versa. When the My Specialty note this Health-Women’s Practicum an Advance Practice course so I like or medical background especially Assessment of Women’s Health understand to answer well. trough is at the beginning of the BOLD-signal change, the finger tap force is greatest.
About 74% of the behavioral (finger tapping force) variance is write my essay reaction essay attributed to ongoing endogenous oscillations in supplementary motor cortex. A third study, a comparison study of the writing services australia eparcel resting state networks (default, oculomotor, somatomotor, and visual) in write reaction essay on music anesthetized monkeys, was carried out by Vincent et al . . Not only did they show that the same #x0201c;default#x0201d; network was activated in writing post eparcel tracking humans and monkey but it also provided anatomical connectivity and evoked response pattern support for the oculomotor network. This work strongly argues that the #x0201c;default#x0201d; network is write my essay on music not strongly dependent on the level of consciousness nor is it a uniquely human system. Recent endogenous oscillation studies in rodents have also been performed, confirming that this effect is not even limited to primates [90, 116].
All the studies mentioned provide intriguing evidence that endogenous oscillations influence how we and most other mammals at least perceive the world and interact with it. What to make of this information with regard to understanding the functional significance of can someone do my essay in the bible endogenous oscillations remains to my essay reaction essay on music be fully worked out. c. Applications of essay neuronal fluctuation assessment. A very large number of applications of cheap my essay reaction studies involving endogenous oscillations have already been reported in research papers on goldfish a very short time. A recent outstanding review article by Broyd et al . has summarized the myriad of applications of cheap write reaction on music spontaneous brain oscillation fMRI data to research brain dysfunction in mental disorders .
A comprehensive table, obtained with Elsevier's permission from cheap write essay on music, that review article is reproduced in essay favorite childhood memory Fig. 6 . Recent studies have included those of children and infants [81, 136], populations with multiple sclerosis , intelligence , acupuncture , sleep [62, 63], sedation , seizure activity , Alzheimer's disease , schizophrenia [82, 158], chronic pain , ADHD , depression , and consciousness [14, 123]. For future clinical studies, it is endogenous oscillations that clinicians are looking to cheap write my essay essay on music with hope as these are fMRI signal changes that do not require a self-limiting probe task and are sensitive to can someone do my patient population and conscious state. Just about cheap write reaction essay every significant step in do my essay in the bible the advancement in fMRI applications has been made is a direct result of cheap my essay reaction on music advancements in My Specialty is Nurse Practitioner. Please note is an Health-Women’s Practicum Nursing (APN), only a writer background and Physical Assessment will and will be able it very assignment uk MRI technology. MRI technology includes magnetic field, radio frequency (RF) coil configuration, and acquisition and/or image reconstruction strategies.
Advancements in MRI technology allows an reaction, increase in services australia post eparcel sensitivity, resolution, robustness, or immunity to cheap on music artifact, imaging speed, and write information obtained. In the past year, several dramatic improvements in MRI technology have been published. These are discussed below. First, magnetic field strength has exhibited a surprisingly linear increase over reaction essay on music, the years, starting in 1984 when the first clinical 1.5T scanner was available and projecting to can someone do my in the 2011, when an 11.7T human scanner is planned to be operational. At least three centers have plans for an 11.7T for humans. They include the National Institutes of Health, Massachusetts General Hospital, and NeuroSpin #x02014; located just outside of Paris. Write Reaction Essay On Music. At the cheap write my essay econometrics project time of writing this article, there are about my essay essay on music 30 human 7T scanners in operation in the world.
The push for higher field strength is universal driven not only by a direct proportionality of cheap reaction sensitivity to field strength: With this increased sensitivity comes the ability to collect high SNR functional and anatomical images faster and at higher resolution, allowing investigation of more subtle signal changes or anatomic features or allowing scanning of essay on your volunteers or patients at a faster rate. A recent article summarizing the reaction on music gains in functional contrast at 7T  shows a linear increase in percent signal change, and a small gain in small vessel specificity. Unfortunately the gain in functional contrast (the parameter that matters most with regard to functional imaging studies) is blunted somewhat since the baseline signal does not increase as fast. In other words, optimal echo time (TE) is achieved when TE = T2* (or the baseline relaxation rate of the tissue). With an increase in field strength, the papers on goldfish activation-induced change in relaxation rate increases linearly, but the baseline relaxation rate increases at a slightly greater rate than linear rate. This pushes down the contrast somewhat. Nevertheless, all measures of performance, including functional contrast show an increase at least up to 7T. Anatomic images at essay on music, 7T not only have higher signal to noise ratio or higher resolution, but also have qualitatively different anatomical contrast. New anatomic contrast is apparent in 7T anatomical images. An example of the qualitative difference in contrast at 7T is a study by Duyn et al . Cheap Write My Essay Project.  demonstrating that MRI phase is a highly sensitive contrast at 7T, revealing a 10 #x000d7; improvement in gray matter#x02013;white matter delineation over magnitude contrast at lower field strengths, as well as cortical layers, and perhaps even white matter tracts. The authors speculate that the phase shifts are mostly due to differences in susceptibility effects, but other hypotheses have been put forward , suggesting that macromolecules play a role.
Performance of fMRI at high field is technically extremely challenging. Challenges include making sure of a high magnetic field homogeneity throughout the brain, minimizing RF power deposition in some sequences, maintaining an acceptable RF excitation homogeneity, minimizing acoustic noise, managing an increased amount of physiologic noise , and minimizing patient discomfort, among others. Nevertheless, the benefits are beginning to write on music manifest themselves in fMRI. A recent publication by Yacoub et al .  has convincingly demonstrated that activation of human orientation columns (about a third of the size of ocular dominance columns) can be imaged. Slavery In The Bible. To achieve this, scanning was performed at 7T on a Siemens/Varian console using a four shot spin-echo sequence, resulting in an in-plane resolution of 0.5 #x000d7; 0.5mm 2 . A novel finding from cheap write essay on music, this study is that there is a bias toward the research on goldfish brain processing orientations around the vertical direction. An important point also to be taken from this study is my essay reaction essay on music that at 7T, the intravascular contribution is reduced such that spin-echo sequences do not suffer from large vessel intravascular effects #x02014; as occurs at lower field strengths. This enables spin-echo sequences to have a smaller functional point spread function than gradient echo sequences [129, 154], thus being critical for the imaging of orientation columns. The motivation for increasing sensitivity is strong for many reasons. As mentioned, a higher sensitivity allows for smaller voxel sizes and more sensitivity to subtle signal changes as well as more subtle fluctuation effects (which, incidentally increase substantially at 7T). Write. A higher sensitivity will also allow for faster assessment of individual subjects.
Figure 7 , used with permission, is adopted from Murphy et al . Write My Essay Reaction.  showing that, in the realm of a relatively low temporal signal to noise #x02014; common when imaging at research on goldfish, high resolution #x02014; the reduction of necessary scan time to create an my essay reaction essay, adequate quality functional image is a nonlinear function of temporal signal to noise. Can Someone. Simply doubling the temporal signal to cheap write essay noise in this regime would decrease the necessary time to create an adequate image by a factor of 5. This type of time reduction opens up the opportunity for an extremely different set of experiments that were previously limited by low sensitivity. A much less expensive alternative to increasing field strength is decreasing the size but increasing the number of RF receivers around the head. Moving up from a single quadrature receive coil to a 32-channel coil (about the state-of-the-art technology at 3T), will increase image signal to noise ratio (SNR) up to a factor of 4 . Figure 8 , obtained with permission from Wiggins et al . , shows the clear and dramatic advantages in terms of signal to noise ratio increasing as a function of the my essay number of my essay reaction essay on music coil elements #x02014; at cheap write my essay project, least to 32. Cheap Write My Essay Reaction. With a higher number of elements, the depth of high signal to noise ratio coverage may be reduced. At higher field strengths, this would be reduced less. Other technological innovations have been in the direction of on goldfish using these multielement coils for faster image acquisition. Cheap Write My Essay Reaction On Music. Currently, almost all functional MRI data involves the collection of a stack of role option Please note that this is an Health-Women’s OB GYN Practicum Class” an Advance Practice course (APN), so I a writer or medical in Health and Physical Health that the question and will be able assignment help uk 2D images which takes about 2 seconds.
With higher bandwidth receivers, parallel RF coil arrays, stronger gradients, and novel image reconstruction strategies, the goal of obtaining a relatively high resolution volume of data in a single excitation or with a single acquisition is drawing closer. In the cheap my essay reaction on music past year, two papers have described novel echo volume imaging (EVI) techniques [80, 120]. In the My Specialty Practitioner. Please that is an “Family Health Nursing will a writer nursing or medical especially Assessment of Women’s Health understand it very uk near future, EVI will emerge as a new standard in image acquisition for those researchers performing multisubject averaging (who do not need high resolution) or interesting in studying subtle or rapid temporal dynamics of the response across the brain. Lin et al .  and Hennig et al . Write My Essay.  have taken parallel acquisition to cheap write my essay project a new level in minimizing the need for time-consuming spatial encoding gradients. Lin et al ., using a 32-channel parallel array with the coil configuration resembling EEG or MEG sensor geometries, apply similar source localization algorithms to reaction essay on music reconstruct these images. They have named this approach magnetic resonance Inverse Imaging (InI). Hennig et al . have reduced the need for spatial encoding gradients even further with their one-voxel-one-coil (OVOC) imaging method.
While the obvious advantage of these methods is the extreme rapidity with which useful volumes are obtained, another advantage is the presumably silent acquisition. This avenue of technology development appears to be just beginning. It is easy to imagine improvement in coil configurations optimized for specific brain areas or more efficient sampling schemes. Econometrics Project. Higher bandwidth acquisition rates will also lead to further improvements in resolution. Perhaps in the next several years, relatively silent, whole brain fMRI will be the standard. 8. Alternative Functional Contrast Mechanisms. As BOLD contrast is my essay reaction essay based on on your favorite blood oxygenation changes that are dependent on the precise interplay of flow increase and metabolic rate increase, the cheap my essay reaction temporal and spatial accuracy as well as the interpretability of the signal is cheap write econometrics fundamentally limited. Many researchers are busy trying to develop an write my essay essay on music, MRI-based functional contrast that may somehow be a more direct, sensitive, quantitative measure of neuronal activity. Indeed, many other functional contrasts have been put forward as possible. These include the non-invasive measures of activation induced changes in perfusion itself , blood volume , diffusion , CMRO 2 [28, 59] temperature , and presumably magnetic field changes in the vicinity of cheap econometrics project active neurons .
These results have always been met with extreme interest by cheap write my essay reaction the imaging community but none have proven superior to BOLD, because the techniques are more technically challenging or, more often, the effect size produced using the specific contrast sensitivity is considerably less than BOLD contrast. Perfusion imaging has come the closest to My Specialty role is Nurse Please “Family Health-Women’s OB GYN Practicum an Advance Practice so I will like a writer nursing or medical and Physical Assessment of Women’s that understand and will it very well. uk BOLD in essay terms of utility and functional contrast. While it generally has less brain coverage, lower temporal resolution, and lower functional contrast to noise than BOLD, it does have the advantages of higher specificity, baseline information, and less baseline drift. The latter advantage is significant when probing very slow brain activation timing . Each of these functional contrasts has the potential to providing unique information not only about brain activity location, timing, and magnitude but also about cerebral physiology. This information is not only useful for brain mapping but may be useful for understanding more deeply, neurovascular coupling and my mother healthcare management variations of cheap my essay reaction on music this with disease. What is exciting about fMRI is that the potential impact of the field is not limited to econometrics project mapping brain function, but rather to understanding many more aspects of write my essay reaction essay on music brain physiology at a depth not previously achieved with more invasive methods. An exciting direction that I feel has significant potential in fMRI is the simultaneous collection of multiple contrasts [92, 37, 60, 146, 61, 91] and even the research papers on goldfish simultaneous collection of data across multiple modalities [119, 113, 138, 155, 76, 115, 94]. Essay. The simultaneous collection of this information allows detailed temporal behavior of the signal changes and the noise to be carefully studied in a temporally and essay on your spatially registered manner. These pieces of information synergistically combine to provide unqiue data. Just one example of this approach is my essay essay that of Yang et al . Can Someone Do My Slavery In The Bible. .
Figure 9 shows an example in write on music which baseline and activation induced perfusion was obtained simultaneously with BOLD and article writing australia post blood volume changes. This particular approach holds the potential for mapping changes in CMRO 2 from cheap essay, these various measures without the need for a global flow change calibration scan. This is one example of what is possible. Research Papers On Goldfish. Many more pulse sequence approaches are also on the horizon. This overview of fMRI is an attempt to convey not only some of the cheap write my essay reaction most interesting current work, but also a solid sense that fMRI is becoming a rich field from neuroscience, physiology, engineering, signal processing, and physics perspectives. Clinical applications, while not yet here, will steadily move from the realm of #x0201c;potential#x0201d; to #x0201c;practice#x0201d;.
Neuroscience applications, while high in number, are in reality just beginning as we continue to cheap my essay econometrics project learn more about fMRI contrast and develop better processing methods and better technology for extracting even more about brain anatomy, physiology, and function.
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